Nucleic Acids

Oligonucleotide Therapeutic Society Oligonucleotide Therapeutic Society- Society host conferences on academia and industry-based research and development of oligonucleotide therapeutics: RNAi, antisense, and others.… Mechanisms of post-transcriptional gene regulation in mammalian cells Mechanisms of post-transcriptional gene regulation in mammalian cells- Description of RNA Interference (RNAi) mechanism, post-transcriptional gene regulation, and RNAi experiments… RNA Interference RNA Interference- Interactive online resource from Howard Hughes Medical Institute. Presents RNAi mechanism and overview of key scientific findings. Article on RNAi by HOPES Article on RNAi by HOPES- Online article describes basic mechanism of RNAi and how it can be applied for Huntington's disease treatment. The RNAi Cure? The RNAi Cure?- A NOVA ScienceNOW science program by PBS feature the possible applications for RNAi therapy. Provides animations of key biological processes and mechanism of RNA I… A TV Show on RNAi by PBS A TV Show on RNAi by PBS- NOVA scienceNOW TV program describes RNAi as a major breakthrough in gene therapy with enormous medical promise. Provides basic overview of RNAi technolo… Technology Networks: Gene Silencing Technology Networks: Gene Silencing- Online resource offering information RNA interference and related issues: news, interviews, articles, techniques. RNAi Therapeutics: How Likely, How Soon? RNAi Therapeutics: How Likely, How Soon?- Review article from PLoS Biology journal. Describes mechanism of RNA Interference, potential applications towards therapeutics, and curre… TargetScan TargetScan- Online software provided by the Whitehead Institute for prediction of microRNA targets. Provides research data and online software for microRNA target identification a… RNAi News RNAi News- Online resource for scientists, researchers, technologists, and executives engaged in RNA Interference, functional genomics, and drug discovery. Offers industry news, p… Fourth Annual Meeting of the Oligonucleotide Therapeutics Society Fourth Annual Meeting of the Oligonucleotide Therapeutics Society- Yearly conference organized by New York Academy of Sciences. Includes information about conference registration,… miRNAMap miRNAMap- Collection of published miRNAs from the microRNA registry and predict putative miRNA precursors based on genome-wide mapping of conserved RNA secondary structures. Discovery on Target Discovery on Target- Annual RNAi meeting hosted by Cambridge Healthcare Institute in Boston, Massachusetts. Online meeting information is available: plenary sessions, exhibits, an… MicroRNA Therapeutics MicroRNA Therapeutics- Online review of microRNA application for leukemia and lung cancer therapeutics by Dr. Dmitri Ovcharenko. CnidBase CnidBase- Provides tools for researchers interested in studying gene expression of these organisms. Includes keyword search of genes and homologs, and a literature scan. The MIT/ICBP siRNA Database The MIT/ICBP siRNA Database- Online resource for researchers looking for experimentally validated siRNAs and shRNAs against target genes, with a focus on genes thought to be invol… Silencing Genomes Silencing Genomes- Portal about genome-wide applications of RNAi by Cold Spring Harbor Laboratory. MicroRNA in Cancer MicroRNA in Cancer- Review of microRNA role in cancer by Nature journal. Provides full-length research papers and reviews. Nature web focus: RNAi Nature web focus: RNAi- Online review of RNA Interference biological phenomena. Includes citations of recent research publications, RNAi animations, and science news articles. Nuclear Receptor Signaling Atlas Nuclear Receptor Signaling Atlas- Informational portal for researchers interested in nuclear receptor signaling. DBTGR - Database of Tunicate Gene Regulation DBTGR - Database of Tunicate Gene Regulation- Gene expression database of tunicates. Provides the descriptions of 12 transcription factors and 140 promoters. RNAi Transfection Resource RNAi Transfection Resource- Review of transfection techniques such as electroporation, denrimers and lipids that are used for transfection of DNA, RNA, and siRNA. Includes informa… Journal of RNAi and Gene Silencing Journal of RNAi and Gene Silencing- Publishes peer-reviewed articles addressing the biology and application of RNA interference and gene silencing. Includes information about jour… Oligoengine Oligoengine- Oligonucleotide design software for applications such as RNAi, DNA methylation, antisense, and genome arrays. RNAi Gateway RNAi Gateway- Web resource from BioMed Central. Provides RNA Interference (RNAi) research highlights, journal links, news, and meeting information. Article on siRNA from Wikipedia Article on siRNA from Wikipedia- Describes small interfering RNA (siRNA) function, structure, use in research, and potential application for therapy. Article on RNAi by GNN Article on RNAi by GNN- Online article describing gene silencing mechanism and how RNAi can be used for HIV treatment. Drosophila RNAi Resource Drosophila RNAi Resource- Informational RNAi resource on studying drosophila genes and their roles in development by Society for Developmental Biology. RNAi Resource at Macalester College RNAi Resource at Macalester College- Informational resource, including RNAi mechanism, overview of current studies, and related research protocols. Gene Silencing Mechanism Gene Silencing Mechanism- Animation of post transcriptional gene silencing or RNA Interference (RNAi) by Nature Reviews Genetics.