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Nucleic Acid and Protein Sequence Analysis Software Nucleic Acid and Protein Sequence Analysis Software- From the Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, USA. VisuMap VisuMap- VisuMap helps to viusalize and undertstand high dimensional by a collection of clustering and mapping algorithms, and many dynamically linked data views. RNAdraw RNAdraw- A program for RNA secondary structure calculation and analysis under 32-bit Microsoft Windows. AiO AiO- Downloadable package integrating database, oligo ordering, DNA and protein analysis programs from Konstanz, Germany. PGEToolbox: A Matlab Toolbox for Population Genetics and Evolution PGEToolbox: A Matlab Toolbox for Population Genetics and Evolution- PGEToolbox enables population genetists to manipulate DNA polymorphism sequences and SNPs, compute basic statis… Qlucore Qlucore- Supplies software to explore and analyze microarray gene expression data sets, in Lund, Sweden. Strand Life Sciences Pvt. Ltd. Strand Life Sciences Pvt. Ltd.- Develops data analysis and visualization software for microarray gene expression data from its base in Bangalore, India. Score Comets Score Comets- Site introducing the comet assay, including equipment needed, hints and tips along with information on the Comet Assay IV software scoring system. MB DNA Analysis MB DNA Analysis- Program for statistical analysis and evaluation of the biological significance from microarray data. Includes key features, registration and download for Windows … The Ribosome Builder Project The Ribosome Builder Project- A software project to simulate the ribosome. Short Time-series Expression Miner Short Time-series Expression Miner- Freeware for clustering, comparing, and visualizing short time series gene expression data, maintained at Carnegie Mellon University, Pittsburg… DNAStar DNAStar- Develops sequence analysis software for molecular biology. DNA Software DNA Software- Company selling software intended for molecular biology. Delila Delila- Software for Analysis of Protein and Nucleic-acid Sequences. Koada Technology Koada Technology- Supplies software for automated analysis and quantification of microarray images. Improved Outcomes Software Inc. Improved Outcomes Software Inc.- Offers programs and custom development for the visualization, analysis and classification of gene expression and proteomics data, image-guided sur… Gene Kinetics Gene Kinetics- Software for transcription and cell cycle genes, providing peak intervals, max values as a function of decay of gene-activating principle, inhibitory mRNA, gene amp… Redasoft Corp. Redasoft Corp.- Makers of restriction enzyme database program, to design cloning experiments and produce high resolution graphics of plasmid maps and alignments. Includes corporat… Oligo Software Oligo Software- Consensus, multiplex and degenerate primers, oligonucleotide database, secondary structure and difficult sequencing for researchers in PCR and related technologies… Chang Bioscience Chang Bioscience- Microarray analysis, lab inventory, and primer sequence database tools from San Francisco, California. Premier Biosoft International Premier Biosoft International- Developers of software for real time PCR primer design, TaqMan, molecular beacons, DNA microarray analysis, drawing restriction plasmid maps, gatewa… Oligonucleotide Therapeutic Society Oligonucleotide Therapeutic Society- Society host conferences on academia and industry-based research and development of oligonucleotide therapeutics: RNAi, antisense, and others.… Mechanisms of post-transcriptional gene regulation in mammalian cells Mechanisms of post-transcriptional gene regulation in mammalian cells- Description of RNA Interference (RNAi) mechanism, post-transcriptional gene regulation, and RNAi experiments… RNA Interference RNA Interference- Interactive online resource from Howard Hughes Medical Institute. Presents RNAi mechanism and overview of key scientific findings. Article on RNAi by HOPES Article on RNAi by HOPES- Online article describes basic mechanism of RNAi and how it can be applied for Huntington's disease treatment. The RNAi Cure? The RNAi Cure?- A NOVA ScienceNOW science program by PBS feature the possible applications for RNAi therapy. Provides animations of key biological processes and mechanism of RNA I… A TV Show on RNAi by PBS A TV Show on RNAi by PBS- NOVA scienceNOW TV program describes RNAi as a major breakthrough in gene therapy with enormous medical promise. Provides basic overview of RNAi technolo… Technology Networks: Gene Silencing Technology Networks: Gene Silencing- Online resource offering information RNA interference and related issues: news, interviews, articles, techniques. RNAi Therapeutics: How Likely, How Soon? RNAi Therapeutics: How Likely, How Soon?- Review article from PLoS Biology journal. Describes mechanism of RNA Interference, potential applications towards therapeutics, and curre… TargetScan TargetScan- Online software provided by the Whitehead Institute for prediction of microRNA targets. Provides research data and online software for microRNA target identification a… RNAi News RNAi News- Online resource for scientists, researchers, technologists, and executives engaged in RNA Interference, functional genomics, and drug discovery. Offers industry news, p… Fourth Annual Meeting of the Oligonucleotide Therapeutics Society Fourth Annual Meeting of the Oligonucleotide Therapeutics Society- Yearly conference organized by New York Academy of Sciences. Includes information about conference registration,… miRNAMap miRNAMap- Collection of published miRNAs from the microRNA registry and predict putative miRNA precursors based on genome-wide mapping of conserved RNA secondary structures. Discovery on Target Discovery on Target- Annual RNAi meeting hosted by Cambridge Healthcare Institute in Boston, Massachusetts. Online meeting information is available: plenary sessions, exhibits, an… MicroRNA Therapeutics MicroRNA Therapeutics- Online review of microRNA application for leukemia and lung cancer therapeutics by Dr. Dmitri Ovcharenko. CnidBase CnidBase- Provides tools for researchers interested in studying gene expression of these organisms. Includes keyword search of genes and homologs, and a literature scan. The MIT/ICBP siRNA Database The MIT/ICBP siRNA Database- Online resource for researchers looking for experimentally validated siRNAs and shRNAs against target genes, with a focus on genes thought to be invol… Silencing Genomes Silencing Genomes- Portal about genome-wide applications of RNAi by Cold Spring Harbor Laboratory. MicroRNA in Cancer MicroRNA in Cancer- Review of microRNA role in cancer by Nature journal. Provides full-length research papers and reviews. Nature web focus: RNAi Nature web focus: RNAi- Online review of RNA Interference biological phenomena. Includes citations of recent research publications, RNAi animations, and science news articles. Nuclear Receptor Signaling Atlas Nuclear Receptor Signaling Atlas- Informational portal for researchers interested in nuclear receptor signaling. DBTGR - Database of Tunicate Gene Regulation DBTGR - Database of Tunicate Gene Regulation- Gene expression database of tunicates. Provides the descriptions of 12 transcription factors and 140 promoters. RNAi Transfection Resource RNAi Transfection Resource- Review of transfection techniques such as electroporation, denrimers and lipids that are used for transfection of DNA, RNA, and siRNA. Includes informa… Journal of RNAi and Gene Silencing Journal of RNAi and Gene Silencing- Publishes peer-reviewed articles addressing the biology and application of RNA interference and gene silencing. Includes information about jour… Oligoengine Oligoengine- Oligonucleotide design software for applications such as RNAi, DNA methylation, antisense, and genome arrays. RNAi Gateway RNAi Gateway- Web resource from BioMed Central. Provides RNA Interference (RNAi) research highlights, journal links, news, and meeting information. Article on siRNA from Wikipedia Article on siRNA from Wikipedia- Describes small interfering RNA (siRNA) function, structure, use in research, and potential application for therapy. Article on RNAi by GNN Article on RNAi by GNN- Online article describing gene silencing mechanism and how RNAi can be used for HIV treatment. Drosophila RNAi Resource Drosophila RNAi Resource- Informational RNAi resource on studying drosophila genes and their roles in development by Society for Developmental Biology. RNAi Resource at Macalester College RNAi Resource at Macalester College- Informational resource, including RNAi mechanism, overview of current studies, and related research protocols.